I'm now on my second play through of Devil May Cry 4 and I'm noticing how much faster I can get through levels and how much more red orbs I can find.  My fist play through I never realized exactly how many items where containers of red and green orbs.  Since you need red orbs to buy items and green orbs recover health it's nice to get these.

I am currently playing through on Devil Hunter mode keeping all the skills and items I got after finishing Human Mode.  So far Devil Mode hasn't felt much more difficult than Human mode except for the boss battles.  In the boss battles I think they give out more damage but that's about the only difference between the two modes. 

I need to play through at Devil Hunter mode because I'm really looking forward to unlocking Bloody Palace mode.  From what I've seen online this mode has 100 stages and you need to kill all the demons on a stage to advance.  You are on a circular platform in the sky just killing everything that spawns.  I think this looks like fun and will open up some new achievements as well.